+ Lead-optimisation-Genotoxicology

Genetic toxicology

A comprehensive range of genetic toxicity services for preclinical assessment and the early screening of candidate compounds. The Genetic Toxicology team works in a purpose-built suite of laboratories and offers a comprehensive selection of genetic toxicity studies.

Introduction

This includes a range of studies suitable for the early screening of candidate compounds.
 

Study Types

  • Bacterial Reverse Mutation Test (Ames Test)
  • Gene Mutation in Mammalian Cells
    • L5178Y TK± Mouse Lymphoma Assay (MLA)
  • Chromosome aberration
    • Human lymphocytes (HL)
  • In Vitro Micronucleus
    • Human lymphocytes
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