+ chemicalsafety-reach-Reproduction-Toxicology

Reproduction Toxicology

World-leading expertise in regulatory and investigative reproduction studies with an enviable heritage spanning 35 years

introduction

Sequani is a world leader in reproduction toxicology with widely recognised expertise across the range of regulatory and investigative reproduction studies. We are unique among the CROs with regard to the volume of reproduction studies we run in comparison to our size, reflecting the huge experience that we have in this area. Reproduction toxicology is a mainstream discipline here at Sequani and has been so for close to 30 years. This depth of experience, supported by extensive background data, enables sound interpretation of results and confident regulatory submission

The highly skilled team of Study Directors is supported by a Principal Reproduction Toxicologist with more than 35 years’ specialist experience. All of our toxicology study directors are cross trained in general and reproduction toxicology - a policy that places us in a unique position for the expert conduct of combined toxicity/reproduction studies and juvenile toxicology studies.  Unrivalled technical expertise is provided by a dedicated foetal pathology group and specialised animal and necropsy technicians.

The foetal pathology staff offer experience in all aspects of foetal evaluation for rats, rabbits, mice and minipigs, including both single and double skeletal staining techniques.

We have a comprehensive historical background database, which we regularly review and update, to support all types of Reproduction Toxicology studies.

Study Types

  • Screening Reproduction/Developmental Toxicology
  • Combined Repeated Dose Toxicity & Reproduction/Developmental Toxicology
  • Pre-Natal Developmental Toxicology
  • 2 Generation Reproduction Toxicology
  • Extended One Generation Reproductive Toxicity Study (OECD 443, EOGRTS)

Dosing Routes

  • Oral gavage
  • Oral dietary
  • Dermal
Our News & Events
Biomarker Validation – Mountain, Molehill or Something in Between?
13 June 2018
Biomarker Validation – Mountain, Molehill or Something in Between?
Read More
More sex, more strain and we are all a bit older…
19 April 2018
Immunophenotyping of lymphocyte subsets
Read More
Moving to Minipigs?
29 March 2018
Moving to Minipigs?
Read More