We have been at the forefront of developing microsampling techniques over the last decade. In light of recent ICH developments, particularly the draft Q&A document for the toxicokinetic guideline (S3A), we have successfully developed a range of applications for micro-blood sample collection that have already been used in over 100 studies across a range of study types. We are proud to offer this approach as a means of reducing animal usage and test item requirement; as well as improving the quality and relevance of toxicokinetic data.